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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HMGCS13-hydroxy-3-methylglutaryl-CoA synthase 1. (520 aa)    
Predicted Functional Partners:
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase.
  
 
 0.999
ACAT2
acetyl-CoA acetyltransferase 2.
  
 0.995
ACAT1
acetyl-CoA acetyltransferase 1.
  
 0.994
ACAA2
acetyl-CoA acyltransferase 2.
  
 0.993
HADHB
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta.
  
 0.993
ACAA1
acetyl-CoA acyltransferase 1.
  
 0.990
ENSNVIP00000001872
Squalene epoxidase.
   
  
 0.967
FDPS
Farnesyl diphosphate synthase.
  
 
 0.967
HMGCL
3-hydroxy-3-methylglutaryl-CoA lyase.
     
 0.963
ACLY
ATP citrate lyase.
   
 
 0.960
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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