Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HMGCS13-hydroxy-3-methylglutaryl-CoA synthase 1. (520 aa)    
Predicted Functional Partners:
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase.
  
 
 0.998
ACAT2
acetyl-CoA acetyltransferase 2.
  
 0.989
HADHB
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta.
  
 0.980
ACAT1
acetyl-CoA acetyltransferase 1.
  
 0.980
ACAA2
acetyl-CoA acyltransferase 2.
  
 0.976
ACAA1
acetyl-CoA acyltransferase 1.
  
 0.973
FDFT1
Farnesyl-diphosphate farnesyltransferase 1.
   
  
 0.967
FDPS
Farnesyl diphosphate synthase.
  
 
 0.964
ENSNVIP00000001872
Squalene epoxidase.
   
  
 0.959
ENSNVIP00000012979
annotation not available
  
  
 0.959
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.