LRIG3 protein (Neovison vison) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

LRIG3

Leucine rich repeats and immunoglobulin like domains 3. (1123 aa)

Predicted Functional Partners:

LRIG1

0.877

ERBB2

0.836

MST1R

0.682

ENSNVIP00000003169

0.682

ENSNVIP00000003233

0.682

RGMB

0.614

RGMA

0.614

HJV

0.614

ROS1

0.612

DCC

0.611

Your Current Organism:

Neovison vison

NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DCC	HJV	ENSNVIP00000003640	ENSNVIP00000031507	DCC netrin 1 receptor.	Hemojuvelin BMP co-receptor.	0.911
DCC	LRIG1	ENSNVIP00000003640	ENSNVIP00000013850	DCC netrin 1 receptor.	Leucine rich repeats and immunoglobulin like domains 1.	0.548
DCC	LRIG3	ENSNVIP00000003640	ENSNVIP00000004416	DCC netrin 1 receptor.	Leucine rich repeats and immunoglobulin like domains 3.	0.611
DCC	RGMA	ENSNVIP00000003640	ENSNVIP00000026436	DCC netrin 1 receptor.	Repulsive guidance molecule BMP co-receptor a.	0.838
DCC	RGMB	ENSNVIP00000003640	ENSNVIP00000002640	DCC netrin 1 receptor.	Repulsive guidance molecule BMP co-receptor b.	0.838
ENSNVIP00000003169	ENSNVIP00000003233	ENSNVIP00000003169	ENSNVIP00000003233	annotation not available	annotation not available	0.653
ENSNVIP00000003169	ERBB2	ENSNVIP00000003169	ENSNVIP00000005168	annotation not available	Erb-b2 receptor tyrosine kinase 2.	0.956
ENSNVIP00000003169	LRIG1	ENSNVIP00000003169	ENSNVIP00000013850	annotation not available	Leucine rich repeats and immunoglobulin like domains 1.	0.977
ENSNVIP00000003169	LRIG3	ENSNVIP00000003169	ENSNVIP00000004416	annotation not available	Leucine rich repeats and immunoglobulin like domains 3.	0.682
ENSNVIP00000003169	MST1R	ENSNVIP00000003169	ENSNVIP00000000620	annotation not available	Macrophage stimulating 1 receptor.	0.691
ENSNVIP00000003233	ENSNVIP00000003169	ENSNVIP00000003233	ENSNVIP00000003169	annotation not available	annotation not available	0.653
ENSNVIP00000003233	ERBB2	ENSNVIP00000003233	ENSNVIP00000005168	annotation not available	Erb-b2 receptor tyrosine kinase 2.	0.905
ENSNVIP00000003233	LRIG1	ENSNVIP00000003233	ENSNVIP00000013850	annotation not available	Leucine rich repeats and immunoglobulin like domains 1.	0.682
ENSNVIP00000003233	LRIG3	ENSNVIP00000003233	ENSNVIP00000004416	annotation not available	Leucine rich repeats and immunoglobulin like domains 3.	0.682
ENSNVIP00000003233	MST1R	ENSNVIP00000003233	ENSNVIP00000000620	annotation not available	Macrophage stimulating 1 receptor.	0.653
ERBB2	ENSNVIP00000003169	ENSNVIP00000005168	ENSNVIP00000003169	Erb-b2 receptor tyrosine kinase 2.	annotation not available	0.956
ERBB2	ENSNVIP00000003233	ENSNVIP00000005168	ENSNVIP00000003233	Erb-b2 receptor tyrosine kinase 2.	annotation not available	0.905
ERBB2	LRIG1	ENSNVIP00000005168	ENSNVIP00000013850	Erb-b2 receptor tyrosine kinase 2.	Leucine rich repeats and immunoglobulin like domains 1.	0.902
ERBB2	LRIG3	ENSNVIP00000005168	ENSNVIP00000004416	Erb-b2 receptor tyrosine kinase 2.	Leucine rich repeats and immunoglobulin like domains 3.	0.836
ERBB2	MST1R	ENSNVIP00000005168	ENSNVIP00000000620	Erb-b2 receptor tyrosine kinase 2.	Macrophage stimulating 1 receptor.	0.899