Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
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[Homology]
Score
CERKCeramide kinase. (498 aa)    
Predicted Functional Partners:
SGMS1
Sphingomyelin synthase 1.
     
 0.950
ACER2
Alkaline ceramidase 2.
    
 0.947
ASAH2
N-acylsphingosine amidohydrolase 2.
    
 0.946
UGCG
UDP-glucose ceramide glucosyltransferase.
     
 0.944
ASAH1
N-acylsphingosine amidohydrolase 1.
     
 0.942
ACER1
Alkaline ceramidase 1.
    
 0.938
GBA2
Glucosylceramidase beta 2.
     
 0.935
CERS2
Ceramide synthase 2.
     
 0.934
PLPP1
Phospholipid phosphatase 1.
  
 
 0.931
SMPD1
Sphingomyelin phosphodiesterase 1.
    
 0.929
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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