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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FZD4Frizzled class receptor 4. (537 aa)    
Predicted Functional Partners:
WNT11
Wnt family member 11.
  
 0.983
ENSNVIP00000020925
Norrin cystine knot growth factor NDP.
    
 
 0.982
LRP6
LDL receptor related protein 6.
    
 0.978
LRP5
LDL receptor related protein 5.
    
 0.978
WNT6
Wnt family member 6.
   
 0.978
WNT1
Wnt family member 1.
    
 0.976
WNT2B
Wnt family member 2B.
    
 0.972
DVL2
Dishevelled segment polarity protein 2.
   
 0.971
WNT2
Wnt family member 2.
  
 
 0.968
RYK
Receptor like tyrosine kinase.
    
 0.967
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.