Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CA8Carbonic anhydrase 8. (290 aa)    
Predicted Functional Partners:
ITPR1
Inositol 1,4,5-trisphosphate receptor type 1.
    
 
 0.902
ZNF236
Zinc finger protein 236.
      
 0.672
HSD17B14
Hydroxysteroid 17-beta dehydrogenase 14.
   
   0.672
VLDLR
Very low density lipoprotein receptor.
      
 0.576
ITPR2
Inositol 1,4,5-trisphosphate receptor type 2.
    
 
 0.552
ITPR3
Inositol 1,4,5-trisphosphate receptor type 3.
    
 
 0.552
CYP24A1
Cytochrome P450 family 24 subfamily A member 1.
   
 
 0.546
GRWD1
Glutamate rich WD repeat containing 1.
   
  
 0.539
WDR43
WD repeat domain 43.
   
    0.526
SLC26A3
Solute carrier family 26 member 3.
   
 
 0.507
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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