HYOU1 protein (Neovison vison) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

HYOU1

Hypoxia up-regulated 1. (1011 aa)

Predicted Functional Partners:

HSPA5

0.996

SIL1

0.988

PDIA4

0.967

ENSNVIP00000018733

0.962

HSP90B1

0.958

SEC63

0.937

PDIA6

0.893

HSPBP1

0.890

CALR

0.870

CRELD2

0.868

Your Current Organism:

Neovison vison

NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CALR	CRELD2	ENSNVIP00000004970	ENSNVIP00000004835	Calreticulin.	Cysteine rich with EGF like domains 2.	0.419
CALR	ENSNVIP00000018733	ENSNVIP00000004970	ENSNVIP00000018733	Calreticulin.	annotation not available	0.892
CALR	HSP90B1	ENSNVIP00000004970	ENSNVIP00000013438	Calreticulin.	Heat shock protein 90 beta family member 1.	0.999
CALR	HSPA5	ENSNVIP00000004970	ENSNVIP00000007569	Calreticulin.	Heat shock protein family A (Hsp70) member 5.	0.984
CALR	HYOU1	ENSNVIP00000004970	ENSNVIP00000004729	Calreticulin.	Hypoxia up-regulated 1.	0.870
CALR	PDIA4	ENSNVIP00000004970	ENSNVIP00000004829	Calreticulin.	Protein disulfide isomerase family A member 4.	0.985
CALR	PDIA6	ENSNVIP00000004970	ENSNVIP00000018745	Calreticulin.	Protein disulfide isomerase family A member 6.	0.951
CALR	SEC63	ENSNVIP00000004970	ENSNVIP00000005397	Calreticulin.	SEC63 homolog, protein translocation regulator.	0.472
CRELD2	CALR	ENSNVIP00000004835	ENSNVIP00000004970	Cysteine rich with EGF like domains 2.	Calreticulin.	0.419
CRELD2	HSP90B1	ENSNVIP00000004835	ENSNVIP00000013438	Cysteine rich with EGF like domains 2.	Heat shock protein 90 beta family member 1.	0.630
CRELD2	HSPA5	ENSNVIP00000004835	ENSNVIP00000007569	Cysteine rich with EGF like domains 2.	Heat shock protein family A (Hsp70) member 5.	0.781
CRELD2	HYOU1	ENSNVIP00000004835	ENSNVIP00000004729	Cysteine rich with EGF like domains 2.	Hypoxia up-regulated 1.	0.868
CRELD2	PDIA4	ENSNVIP00000004835	ENSNVIP00000004829	Cysteine rich with EGF like domains 2.	Protein disulfide isomerase family A member 4.	0.888
CRELD2	PDIA6	ENSNVIP00000004835	ENSNVIP00000018745	Cysteine rich with EGF like domains 2.	Protein disulfide isomerase family A member 6.	0.825
ENSNVIP00000018733	CALR	ENSNVIP00000018733	ENSNVIP00000004970	annotation not available	Calreticulin.	0.892
ENSNVIP00000018733	HSP90B1	ENSNVIP00000018733	ENSNVIP00000013438	annotation not available	Heat shock protein 90 beta family member 1.	0.968
ENSNVIP00000018733	HSPBP1	ENSNVIP00000018733	ENSNVIP00000015391	annotation not available	HSPA (Hsp70) binding protein 1.	0.796
ENSNVIP00000018733	HYOU1	ENSNVIP00000018733	ENSNVIP00000004729	annotation not available	Hypoxia up-regulated 1.	0.962
ENSNVIP00000018733	PDIA4	ENSNVIP00000018733	ENSNVIP00000004829	annotation not available	Protein disulfide isomerase family A member 4.	0.883
ENSNVIP00000018733	PDIA6	ENSNVIP00000018733	ENSNVIP00000018745	annotation not available	Protein disulfide isomerase family A member 6.	0.567