DNASE2 protein (Neovison vison) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

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experimentally determined

co-expression

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gene neighborhood

gene co-occurrence

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[Homology]

Score

DNASE2

Deoxyribonuclease 2, lysosomal. (359 aa)

Predicted Functional Partners:

DNASE2B

0.964

CTSZ

0.867

RRM1

0.801

GNS

0.705

ENSNVIP00000025793

0.671

VAMP8

0.593

ENSNVIP00000028201

0.592

CTSB

0.582

M6PR

0.564

ENSNVIP00000027519

0.559

Your Current Organism:

Neovison vison

NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTSB	CTSZ	ENSNVIP00000027894	ENSNVIP00000028298	Cathepsin B.	Cathepsin Z.	0.895
CTSB	DNASE2	ENSNVIP00000027894	ENSNVIP00000004831	Cathepsin B.	Deoxyribonuclease 2, lysosomal.	0.582
CTSB	DNASE2B	ENSNVIP00000027894	ENSNVIP00000011726	Cathepsin B.	Deoxyribonuclease 2 beta.	0.582
CTSB	ENSNVIP00000027519	ENSNVIP00000027894	ENSNVIP00000027519	Cathepsin B.	SH3 domain containing GRB2 like 2, endophilin A1.	0.439
CTSB	ENSNVIP00000028201	ENSNVIP00000027894	ENSNVIP00000028201	Cathepsin B.	annotation not available	0.563
CTSB	GNS	ENSNVIP00000027894	ENSNVIP00000011273	Cathepsin B.	Glucosamine (N-acetyl)-6-sulfatase.	0.432
CTSB	M6PR	ENSNVIP00000027894	ENSNVIP00000010029	Cathepsin B.	Mannose-6-phosphate receptor, cation dependent.	0.556
CTSB	VAMP8	ENSNVIP00000027894	ENSNVIP00000023992	Cathepsin B.	Vesicle associated membrane protein 8.	0.552
CTSZ	CTSB	ENSNVIP00000028298	ENSNVIP00000027894	Cathepsin Z.	Cathepsin B.	0.895
CTSZ	DNASE2	ENSNVIP00000028298	ENSNVIP00000004831	Cathepsin Z.	Deoxyribonuclease 2, lysosomal.	0.867
CTSZ	DNASE2B	ENSNVIP00000028298	ENSNVIP00000011726	Cathepsin Z.	Deoxyribonuclease 2 beta.	0.764
CTSZ	ENSNVIP00000027519	ENSNVIP00000028298	ENSNVIP00000027519	Cathepsin Z.	SH3 domain containing GRB2 like 2, endophilin A1.	0.489
CTSZ	ENSNVIP00000028201	ENSNVIP00000028298	ENSNVIP00000028201	Cathepsin Z.	annotation not available	0.656
CTSZ	GNS	ENSNVIP00000028298	ENSNVIP00000011273	Cathepsin Z.	Glucosamine (N-acetyl)-6-sulfatase.	0.638
CTSZ	M6PR	ENSNVIP00000028298	ENSNVIP00000010029	Cathepsin Z.	Mannose-6-phosphate receptor, cation dependent.	0.687
CTSZ	VAMP8	ENSNVIP00000028298	ENSNVIP00000023992	Cathepsin Z.	Vesicle associated membrane protein 8.	0.703
DNASE2	CTSB	ENSNVIP00000004831	ENSNVIP00000027894	Deoxyribonuclease 2, lysosomal.	Cathepsin B.	0.582
DNASE2	CTSZ	ENSNVIP00000004831	ENSNVIP00000028298	Deoxyribonuclease 2, lysosomal.	Cathepsin Z.	0.867
DNASE2	DNASE2B	ENSNVIP00000004831	ENSNVIP00000011726	Deoxyribonuclease 2, lysosomal.	Deoxyribonuclease 2 beta.	0.964
DNASE2	ENSNVIP00000025793	ENSNVIP00000004831	ENSNVIP00000025793	Deoxyribonuclease 2, lysosomal.	annotation not available	0.671