Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ARIH1Ariadne RBR E3 ubiquitin protein ligase 1. (555 aa)    
Predicted Functional Partners:
CUL3
Cullin 3.
   
 0.976
UBE2L6
Ubiquitin conjugating enzyme E2 L6.
   
 0.964
ENSNVIP00000008604
annotation not available
    
 0.956
RBX1
Ring-box 1.
    
 0.955
ENSNVIP00000003240
annotation not available
    
  0.936
UBA52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
  0.936
RPS27A
Ribosomal protein S27a.
    
  0.935
ENSNVIP00000022379
annotation not available
    
  0.935
ENSNVIP00000030368
Ubiquitin conjugating enzyme E2 D1.
   
 0.933
CUL1
Cullin 1.
   
 0.917
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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