Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GHRGrowth hormone receptor. (645 aa)    
Predicted Functional Partners:
JAK2
Janus kinase 2.
    
 0.991
ENSNVIP00000030703
Somatotropin.
    
 0.986
JAK3
Janus kinase 3.
    
 0.980
STAT5A
Signal transducer and activator of transcription 5A.
    
 0.970
JAK1
Janus kinase 1.
    
 0.961
STAT5B
Signal transducer and activator of transcription 5B.
    
 0.955
SOCS2
Suppressor of cytokine signaling 2.
    
 0.955
PRL
Prolactin.
     
 0.953
ENSNVIP00000013505
Leptin receptor.
  
  
 0.917
TYK2
Tyrosine kinase 2.
    
 0.916
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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