Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSNVIP00000004961Suppressor of cytokine signaling 4. (441 aa)    
Predicted Functional Partners:
ENSNVIP00000031731
Cullin 5.
   
 0.958
JAK1
Janus kinase 1.
    
 0.949
JAK3
Janus kinase 3.
    
 0.949
JAK2
Janus kinase 2.
    
 0.949
TYK2
Tyrosine kinase 2.
    
 0.949
ENSNVIP00000017738
Suppressor of cytokine signaling 3.
     
0.948
SOCS2
Suppressor of cytokine signaling 2.
     
0.937
STAT1
Signal transducer and activator of transcription 1.
    
 0.934
SOCS1
Suppressor of cytokine signaling 1.
     
0.928
STAT3
Signal transducer and activator of transcription 3.
    
 0.902
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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