Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GRK3G protein-coupled receptor kinase 3. (687 aa)    
Predicted Functional Partners:
SMO
Smoothened, frizzled class receptor.
    
 0.966
OPRM1
Opioid receptor mu 1.
    
 0.898
CXCR4
C-X-C motif chemokine receptor 4.
    
 0.898
ENSNVIP00000027695
annotation not available
    
 0.896
CCR5
C-C motif chemokine receptor 5 (gene/pseudogene).
    
 0.896
CCR3
C-C motif chemokine receptor 3.
    
 0.893
CXCR3
C-X-C motif chemokine receptor 3.
    
 0.891
CCR7
C-C motif chemokine receptor 7.
    
 0.890
OR51D1
Olfactory receptor family 51 subfamily D member 1.
    
 0.889
CSNK1A1
Casein kinase 1 alpha 1.
     
 0.888
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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