Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PRKD1Protein kinase D1. (920 aa)    
Predicted Functional Partners:
PRKD3
Protein kinase D3.
   
  0.982
ENSNVIP00000001371
RAP1A, member of RAS oncogene family.
     
 0.921
RAP1B
RAP1B, member of RAS oncogene family.
     
 0.921
ATF2
Activating transcription factor 2.
     
 0.894
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
   
 
  0.889
CREB1
cAMP responsive element binding protein 1.
     
 0.888
PKD1
Polycystin 1, transient receptor potential channel interacting.
    
 
 0.888
PRKCA
Protein kinase C alpha.
    
 0.887
PRKCD
Protein kinase C delta.
   
 0.887
ITGB2
Integrin subunit beta 2.
    
  0.885
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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