STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SH2B1SH2B adaptor protein 1. (757 aa)    
Predicted Functional Partners:
CBL
Cbl proto-oncogene.
    
 0.958
GRB2
Growth factor receptor bound protein 2.
    
 0.958
NTRK2
Neurotrophic receptor tyrosine kinase 2.
    
 0.932
INSR
Insulin receptor.
    
 0.927
NTRK3
Neurotrophic receptor tyrosine kinase 3.
    
 0.926
JAK2
Janus kinase 2.
    
 0.919
CBLB
Cbl proto-oncogene B.
    
 0.910
NTRK1
Neurotrophic receptor tyrosine kinase 1.
    
 0.909
SH2B3
SH2B adaptor protein 3.
    
 0.890
IGF1R
Insulin like growth factor 1 receptor.
    
 0.817
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.