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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APC2APC regulator of WNT signaling pathway 2. (2201 aa)    
Predicted Functional Partners:
ENSNVIP00000031759
Catenin beta 1.
   
 0.984
AXIN1
Axin 1.
   
 0.976
AXIN2
Axin 2.
   
 0.969
ARHGEF4
Rho guanine nucleotide exchange factor 4.
   
 0.969
GSK3B
Glycogen synthase kinase 3 beta.
    
 0.961
ENSNVIP00000031787
annotation not available
   
 0.938
CSNK1A1
Casein kinase 1 alpha 1.
    
 0.911
DVL2
Dishevelled segment polarity protein 2.
    
 0.908
DVL1
Dishevelled segment polarity protein 1.
    
 0.908
DVL3
Dishevelled segment polarity protein 3.
    
 0.904
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.