MEGF6 protein (Neovison vison) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

MEGF6

Multiple EGF like domains 6. (1178 aa)

Predicted Functional Partners:

WRAP73

0.621

HMGXB4

0.568

LTN1

0.567

RITA1

0.562

ZBTB40

0.521

CTNNAL1

0.502

RHEBL1

0.500

SERINC2

0.481

ENSNVIP00000025701

0.451

ENSNVIP00000003292

0.437

Your Current Organism:

Neovison vison

NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTNNAL1	MEGF6	ENSNVIP00000009232	ENSNVIP00000005304	Catenin alpha like 1.	Multiple EGF like domains 6.	0.502
ENSNVIP00000003292	MEGF6	ENSNVIP00000003292	ENSNVIP00000005304	annotation not available	Multiple EGF like domains 6.	0.437
ENSNVIP00000025701	MEGF6	ENSNVIP00000025701	ENSNVIP00000005304	U-box domain containing 5.	Multiple EGF like domains 6.	0.451
HMGXB4	MEGF6	ENSNVIP00000005254	ENSNVIP00000005304	HMG-box containing 4.	Multiple EGF like domains 6.	0.568
LTN1	MEGF6	ENSNVIP00000004830	ENSNVIP00000005304	Listerin E3 ubiquitin protein ligase 1.	Multiple EGF like domains 6.	0.567
MEGF6	CTNNAL1	ENSNVIP00000005304	ENSNVIP00000009232	Multiple EGF like domains 6.	Catenin alpha like 1.	0.502
MEGF6	ENSNVIP00000003292	ENSNVIP00000005304	ENSNVIP00000003292	Multiple EGF like domains 6.	annotation not available	0.437
MEGF6	ENSNVIP00000025701	ENSNVIP00000005304	ENSNVIP00000025701	Multiple EGF like domains 6.	U-box domain containing 5.	0.451
MEGF6	HMGXB4	ENSNVIP00000005304	ENSNVIP00000005254	Multiple EGF like domains 6.	HMG-box containing 4.	0.568
MEGF6	LTN1	ENSNVIP00000005304	ENSNVIP00000004830	Multiple EGF like domains 6.	Listerin E3 ubiquitin protein ligase 1.	0.567
MEGF6	RHEBL1	ENSNVIP00000005304	ENSNVIP00000008614	Multiple EGF like domains 6.	RHEB like 1.	0.500
MEGF6	RITA1	ENSNVIP00000005304	ENSNVIP00000019400	Multiple EGF like domains 6.	RBPJ interacting and tubulin associated 1.	0.562
MEGF6	SERINC2	ENSNVIP00000005304	ENSNVIP00000031419	Multiple EGF like domains 6.	Serine incorporator 2.	0.481
MEGF6	WRAP73	ENSNVIP00000005304	ENSNVIP00000005350	Multiple EGF like domains 6.	WD repeat containing, antisense to TP73.	0.621
MEGF6	ZBTB40	ENSNVIP00000005304	ENSNVIP00000029286	Multiple EGF like domains 6.	Zinc finger and BTB domain containing 40.	0.521
RHEBL1	MEGF6	ENSNVIP00000008614	ENSNVIP00000005304	RHEB like 1.	Multiple EGF like domains 6.	0.500
RHEBL1	SERINC2	ENSNVIP00000008614	ENSNVIP00000031419	RHEB like 1.	Serine incorporator 2.	0.530
RITA1	MEGF6	ENSNVIP00000019400	ENSNVIP00000005304	RBPJ interacting and tubulin associated 1.	Multiple EGF like domains 6.	0.562
SERINC2	MEGF6	ENSNVIP00000031419	ENSNVIP00000005304	Serine incorporator 2.	Multiple EGF like domains 6.	0.481
SERINC2	RHEBL1	ENSNVIP00000031419	ENSNVIP00000008614	Serine incorporator 2.	RHEB like 1.	0.530