PNMT protein (Neovison vison) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

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experimentally determined

co-expression

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gene neighborhood

gene co-occurrence

gene fusions

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[Homology]

Score

PNMT

Phenylethanolamine N-methyltransferase. (283 aa)

Predicted Functional Partners:

DBH

0.966

COMT

0.930

ENSNVIP00000026496

0.914

MAOA

0.906

MAOB

0.906

AANAT

0.797

DDC

0.796

MOXD1

0.789

ENSNVIP00000026812

0.789

NAMPT

0.774

Your Current Organism:

Neovison vison

NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AANAT	DDC	ENSNVIP00000016224	ENSNVIP00000023517	Aralkylamine N-acetyltransferase.	Dopa decarboxylase.	0.931
AANAT	MAOA	ENSNVIP00000016224	ENSNVIP00000020847	Aralkylamine N-acetyltransferase.	Monoamine oxidase A.	0.901
AANAT	MAOB	ENSNVIP00000016224	ENSNVIP00000020884	Aralkylamine N-acetyltransferase.	Monoamine oxidase B.	0.901
AANAT	PNMT	ENSNVIP00000016224	ENSNVIP00000005313	Aralkylamine N-acetyltransferase.	Phenylethanolamine N-methyltransferase.	0.797
COMT	DBH	ENSNVIP00000029412	ENSNVIP00000025640	catechol-O-methyltransferase.	Dopamine beta-hydroxylase.	0.944
COMT	DDC	ENSNVIP00000029412	ENSNVIP00000023517	catechol-O-methyltransferase.	Dopa decarboxylase.	0.945
COMT	ENSNVIP00000026496	ENSNVIP00000029412	ENSNVIP00000026496	catechol-O-methyltransferase.	annotation not available	0.928
COMT	ENSNVIP00000026812	ENSNVIP00000029412	ENSNVIP00000026812	catechol-O-methyltransferase.	annotation not available	0.747
COMT	MAOA	ENSNVIP00000029412	ENSNVIP00000020847	catechol-O-methyltransferase.	Monoamine oxidase A.	0.956
COMT	MAOB	ENSNVIP00000029412	ENSNVIP00000020884	catechol-O-methyltransferase.	Monoamine oxidase B.	0.956
COMT	MOXD1	ENSNVIP00000029412	ENSNVIP00000025386	catechol-O-methyltransferase.	Monooxygenase DBH like 1.	0.747
COMT	PNMT	ENSNVIP00000029412	ENSNVIP00000005313	catechol-O-methyltransferase.	Phenylethanolamine N-methyltransferase.	0.930
DBH	COMT	ENSNVIP00000025640	ENSNVIP00000029412	Dopamine beta-hydroxylase.	catechol-O-methyltransferase.	0.944
DBH	DDC	ENSNVIP00000025640	ENSNVIP00000023517	Dopamine beta-hydroxylase.	Dopa decarboxylase.	0.943
DBH	ENSNVIP00000026496	ENSNVIP00000025640	ENSNVIP00000026496	Dopamine beta-hydroxylase.	annotation not available	0.930
DBH	MAOA	ENSNVIP00000025640	ENSNVIP00000020847	Dopamine beta-hydroxylase.	Monoamine oxidase A.	0.928
DBH	MAOB	ENSNVIP00000025640	ENSNVIP00000020884	Dopamine beta-hydroxylase.	Monoamine oxidase B.	0.928
DBH	PNMT	ENSNVIP00000025640	ENSNVIP00000005313	Dopamine beta-hydroxylase.	Phenylethanolamine N-methyltransferase.	0.966
DDC	AANAT	ENSNVIP00000023517	ENSNVIP00000016224	Dopa decarboxylase.	Aralkylamine N-acetyltransferase.	0.931
DDC	COMT	ENSNVIP00000023517	ENSNVIP00000029412	Dopa decarboxylase.	catechol-O-methyltransferase.	0.945