Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
COPS4COP9 signalosome subunit 4. (366 aa)    
Predicted Functional Partners:
GPS1
G protein pathway suppressor 1.
   
 0.999
COPS2
COP9 signalosome subunit 2.
   
 0.999
COPS3
COP9 signalosome subunit 3.
   
 0.999
COPS6
COP9 signalosome subunit 6.
   
 0.998
ENSNVIP00000004019
COP9 signalosome subunit 7B.
   
 0.996
ENSNVIP00000032000
COP9 signalosome subunit 7A.
   
 0.996
ENSNVIP00000007729
annotation not available
   
 0.992
ENSNVIP00000029468
annotation not available
   
 0.992
COPS5
COP9 signalosome subunit 5.
   
 0.988
DDB2
Damage specific DNA binding protein 2.
    
 0.983
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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