Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HIPK3Homeodomain interacting protein kinase 3. (1224 aa)    
Predicted Functional Partners:
HIPK1
Homeodomain interacting protein kinase 1.
   
  0.977
TP53
Tumor protein p53.
    
 0.960
HIPK2
Homeodomain interacting protein kinase 2.
   
 
  0.949
HIPK4
Homeodomain interacting protein kinase 4.
   
  0.931
RASSF5
Ras association domain family member 5.
    
 0.892
DAXX
Death domain associated protein.
    
 
 0.681
UBE2I
Ubiquitin conjugating enzyme E2 I.
    
 0.679
DCAF7
DDB1 and CUL4 associated factor 7.
   
 
 0.665
MECP2
methyl-CpG binding protein 2.
    
 0.635
EP300
E1A binding protein p300.
   
 0.618
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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