Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PRKCZProtein kinase C zeta. (580 aa)    
Predicted Functional Partners:
PARD6A
Par-6 family cell polarity regulator alpha.
    
 0.986
PARD3
Par-3 family cell polarity regulator.
    
 0.986
LLGL2
LLGL scribble cell polarity complex component 2.
    
 0.984
LLGL1
LLGL scribble cell polarity complex component 1.
    
 0.984
PIAS4
Protein inhibitor of activated STAT 4.
    
 0.934
PARD6B
Par-6 family cell polarity regulator beta.
    
 0.934
PARD6G
Par-6 family cell polarity regulator gamma.
    
 0.934
RAC2
Rac family small GTPase 2.
    
 0.927
SQSTM1
Sequestosome 1.
    
 0.925
GSK3B
Glycogen synthase kinase 3 beta.
    
 0.920
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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