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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRKCZProtein kinase C zeta. (580 aa)    
Predicted Functional Partners:
PARD6A
Par-6 family cell polarity regulator alpha.
    
 0.990
PARD3
Par-3 family cell polarity regulator.
    
 0.988
LLGL1
LLGL scribble cell polarity complex component 1.
    
 0.984
LLGL2
LLGL scribble cell polarity complex component 2.
    
 0.982
PARD6B
Par-6 family cell polarity regulator beta.
    
 0.968
PARD6G
Par-6 family cell polarity regulator gamma.
    
 0.968
RAC2
Rac family small GTPase 2.
   
 0.954
PIK3CA
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha.
   
 0.949
ENSNVIP00000004958
annotation not available
    
 0.947
TP53
Tumor protein p53.
    
 0.946
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.