Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IBTKInhibitor of Bruton tyrosine kinase. (1352 aa)    
Predicted Functional Partners:
CUL3
Cullin 3.
   
 0.955
ENSNVIP00000001792
POP7 homolog, ribonuclease P/MRP subunit.
    
   0.937
BTK
Bruton tyrosine kinase.
   
 
 0.918
RPP25L
Ribonuclease P/MRP subunit p25 like.
    
 
 0.887
EIF4A1
Eukaryotic translation initiation factor 4A1.
    
 
 0.874
ANKRD9
Ankyrin repeat domain 9.
    
 0.759
DNAJC17
DnaJ heat shock protein family (Hsp40) member C17.
      
 0.754
CUL1
Cullin 1.
   
 0.751
BMX
BMX non-receptor tyrosine kinase.
   
 
 0.741
EIF4A2
Eukaryotic translation initiation factor 4A2.
    
   0.731
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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