STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTPN22Protein tyrosine phosphatase non-receptor type 22. (805 aa)    
Predicted Functional Partners:
CSK
C-terminal Src kinase.
   
 0.961
EGFR
Epidermal growth factor receptor.
    
 0.930
PSTPIP1
Proline-serine-threonine phosphatase interacting protein 1.
   
 
 0.911
PSTPIP2
Proline-serine-threonine phosphatase interacting protein 2.
   
 
 0.860
SHC3
SHC adaptor protein 3.
   
 0.836
SHC1
SHC adaptor protein 1.
   
 0.836
MATK
Megakaryocyte-associated tyrosine kinase.
   
 0.805
BCAR1
BCAR1 scaffold protein, Cas family member.
    
 
 0.773
ZAP70
Zeta chain of T cell receptor associated protein kinase 70.
   
 0.721
HCK
HCK proto-oncogene, Src family tyrosine kinase.
   
 0.695
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
Server load: medium (80%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.