Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TIAM1TIAM Rac1 associated GEF 1. (1591 aa)    
Predicted Functional Partners:
PARD3
Par-3 family cell polarity regulator.
    
 0.975
RAC2
Rac family small GTPase 2.
    
 0.961
CD44
CD44 molecule (Indian blood group).
    
 0.932
VAV2
Vav guanine nucleotide exchange factor 2.
     
 0.928
RAC1
Rac family small GTPase 1.
    
 0.927
PAK1
P21 (RAC1) activated kinase 1.
   
 0.926
RAC3
Rac family small GTPase 3.
    
 0.922
VAV1
Vav guanine nucleotide exchange factor 1.
     
 0.907
VAV3
Vav guanine nucleotide exchange factor 3.
     
 0.904
PRKCZ
Protein kinase C zeta.
    
 0.901
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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