Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DKK3Dickkopf WNT signaling pathway inhibitor 3. (348 aa)    
Predicted Functional Partners:
DKK2
Dickkopf WNT signaling pathway inhibitor 2.
      
 0.753
DKK1
Dickkopf WNT signaling pathway inhibitor 1.
      
 0.730
WNT6
Wnt family member 6.
    
 0.619
SFRP4
Secreted frizzled related protein 4.
   
 
 0.614
FZD10
Frizzled class receptor 10.
    
 
 0.569
ENSNVIP00000009061
annotation not available
    
 0.556
DKK4
Dickkopf WNT signaling pathway inhibitor 4.
      
 0.549
LRP5
LDL receptor related protein 5.
    
 0.535
WIF1
WNT inhibitory factor 1.
      
 0.512
SFRP2
Secreted frizzled related protein 2.
    
 
 0.488
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.