Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PCSK1Proprotein convertase subtilisin/kexin type 1. (753 aa)    
Predicted Functional Partners:
GHRL
Ghrelin and obestatin prepropeptide.
     
 0.916
SLC30A8
Solute carrier family 30 member 8.
   
 
 0.760
ENSNVIP00000009722
annotation not available
     
 0.758
INS
Insulin.
     
 0.758
ENSNVIP00000010368
Barttin CLCNK type accessory beta subunit.
      
 0.754
USP24
Ubiquitin specific peptidase 24.
      
 0.754
FAP
Fibroblast activation protein alpha.
   
 
 0.736
ENSNVIP00000008576
Glucagon.
   
 
 0.736
LDLR
Low density lipoprotein receptor.
      
 0.725
GLP1R
Glucagon like peptide 1 receptor.
      
 0.669
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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