Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSNVIP00000006058RAD9-HUS1-RAD1 interacting nuclear orphan 1. (255 aa)    
Predicted Functional Partners:
TOPBP1
DNA topoisomerase II binding protein 1.
    
 0.992
RAD1
RAD1 checkpoint DNA exonuclease.
   
 0.980
ENSNVIP00000028766
annotation not available
    
 0.944
RAD9A
RAD9 checkpoint clamp component A.
    
 0.938
CLSPN
Claspin.
     
 0.907
ENSNVIP00000006977
SMC5-SMC6 complex localization factor 1.
    
 0.890
RAD9B
RAD9 checkpoint clamp component B.
    
 0.846
ENSNVIP00000026123
Checkpoint kinase 1.
   
 
 0.814
WRN
WRN RecQ like helicase.
     
 0.741
ATR
ATR serine/threonine kinase.
     
 0.705
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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