Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HIPK1Homeodomain interacting protein kinase 1. (1210 aa)    
Predicted Functional Partners:
HIPK2
Homeodomain interacting protein kinase 2.
   
  0.994
HIPK3
Homeodomain interacting protein kinase 3.
   
  0.977
TP53
Tumor protein p53.
    
 0.960
RASSF5
Ras association domain family member 5.
    
 0.903
ENSNVIP00000016878
Four and a half LIM domains 3.
    
 
 0.746
HIPK4
Homeodomain interacting protein kinase 4.
     
 0.723
PML
Promyelocytic leukemia.
    
 
 0.704
DAXX
Death domain associated protein.
    
 
 0.681
UBE2I
Ubiquitin conjugating enzyme E2 I.
    
 0.679
DCAF7
DDB1 and CUL4 associated factor 7.
   
 
 0.665
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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