Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BACE2Beta-secretase 2. (653 aa)    
Predicted Functional Partners:
RTN3
Reticulon 3.
    
 0.930
RTN4
Reticulon 4.
    
 0.928
APP
Amyloid beta precursor protein.
    
 0.922
BACE1
Beta-secretase 1.
     
  0.882
APLP2
Amyloid beta precursor like protein 2.
    
 0.759
ENSNVIP00000004768
annotation not available
     
  0.721
WFDC2
WAP four-disulfide core domain 2.
   
   0.714
GGA1
Golgi associated, gamma adaptin ear containing, ARF binding protein 1.
    
 0.707
ENSNVIP00000003900
annotation not available
    
 0.707
RTN2
Reticulon 2.
    
 0.702
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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