STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HERC2HECT and RLD domain containing E3 ubiquitin protein ligase 2. (4834 aa)    
Predicted Functional Partners:
RNF8
Ring finger protein 8.
    
 0.972
ENSNVIP00000003579
annotation not available
    
 
 0.954
BRCA1
BRCA1 DNA repair associated.
    
 0.935
UBE3A
Ubiquitin protein ligase E3A.
   
 0.927
NCOA4
Nuclear receptor coactivator 4.
    
 
 0.897
MAPK6
Mitogen-activated protein kinase 6.
    
 0.891
TP53
Tumor protein p53.
   
 
 0.888
USP16
Ubiquitin specific peptidase 16.
    
 
 0.886
USP20
Ubiquitin specific peptidase 20.
   
 
 0.879
CEP170
Centrosomal protein 170.
    
 
 0.875
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.