Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MKNK2MAPK interacting serine/threonine kinase 2. (466 aa)    
Predicted Functional Partners:
MAPK3
Mitogen-activated protein kinase 3.
    
 0.958
MAPK1
Mitogen-activated protein kinase 1.
    
 0.958
EIF4E1B
Eukaryotic translation initiation factor 4E family member 1B.
    
 0.950
ENSNVIP00000005094
annotation not available
    
 0.913
ENSNVIP00000008427
annotation not available
    
 0.913
ATF4
Activating transcription factor 4.
     
 0.883
EIF4E2
Eukaryotic translation initiation factor 4E family member 2.
     
  0.882
MKNK1
MAPK interacting serine/threonine kinase 1.
     
  0.882
MAPK7
Mitogen-activated protein kinase 7.
    
 0.830
MAPK11
Mitogen-activated protein kinase 11.
    
  0.732
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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