MKX protein (Neovison vison) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

MKX

Mohawk homeobox. (353 aa)

Predicted Functional Partners:

IRX1

0.841

IRX6

0.841

TNMD

0.719

IRX4

0.678

HOXD10

0.540

MEOX2

0.536

DCN

0.530

TCF15

0.520

EGR1

0.516

HHEX

0.510

Your Current Organism:

Neovison vison

NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink

Export your current network:

... as a bitmap image:

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file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

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same PNG format, but at higher resolution

... as a vector graphic:

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DCN	MKX	ENSNVIP00000031080	ENSNVIP00000006276	Decorin.	Mohawk homeobox.	0.530
DCN	TNMD	ENSNVIP00000031080	ENSNVIP00000007370	Decorin.	Tenomodulin.	0.665
EGR1	MKX	ENSNVIP00000018763	ENSNVIP00000006276	Early growth response 1.	Mohawk homeobox.	0.516
EGR1	TNMD	ENSNVIP00000018763	ENSNVIP00000007370	Early growth response 1.	Tenomodulin.	0.423
HHEX	IRX1	ENSNVIP00000027417	ENSNVIP00000000044	Hematopoietically expressed homeobox.	Iroquois homeobox 1.	0.513
HHEX	MKX	ENSNVIP00000027417	ENSNVIP00000006276	Hematopoietically expressed homeobox.	Mohawk homeobox.	0.510
HOXD10	MKX	ENSNVIP00000009036	ENSNVIP00000006276	Homeobox D10.	Mohawk homeobox.	0.540
IRX1	HHEX	ENSNVIP00000000044	ENSNVIP00000027417	Iroquois homeobox 1.	Hematopoietically expressed homeobox.	0.513
IRX1	IRX4	ENSNVIP00000000044	ENSNVIP00000031694	Iroquois homeobox 1.	Iroquois homeobox 4.	0.800
IRX1	IRX6	ENSNVIP00000000044	ENSNVIP00000021930	Iroquois homeobox 1.	Iroquois homeobox 6.	0.969
IRX1	MKX	ENSNVIP00000000044	ENSNVIP00000006276	Iroquois homeobox 1.	Mohawk homeobox.	0.841
IRX4	IRX1	ENSNVIP00000031694	ENSNVIP00000000044	Iroquois homeobox 4.	Iroquois homeobox 1.	0.800
IRX4	MKX	ENSNVIP00000031694	ENSNVIP00000006276	Iroquois homeobox 4.	Mohawk homeobox.	0.678
IRX6	IRX1	ENSNVIP00000021930	ENSNVIP00000000044	Iroquois homeobox 6.	Iroquois homeobox 1.	0.969
IRX6	MKX	ENSNVIP00000021930	ENSNVIP00000006276	Iroquois homeobox 6.	Mohawk homeobox.	0.841
MEOX2	MKX	ENSNVIP00000019339	ENSNVIP00000006276	Mesenchyme homeobox 2.	Mohawk homeobox.	0.536
MKX	DCN	ENSNVIP00000006276	ENSNVIP00000031080	Mohawk homeobox.	Decorin.	0.530
MKX	EGR1	ENSNVIP00000006276	ENSNVIP00000018763	Mohawk homeobox.	Early growth response 1.	0.516
MKX	HHEX	ENSNVIP00000006276	ENSNVIP00000027417	Mohawk homeobox.	Hematopoietically expressed homeobox.	0.510
MKX	HOXD10	ENSNVIP00000006276	ENSNVIP00000009036	Mohawk homeobox.	Homeobox D10.	0.540