Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-expression
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[Homology]
Score
DENND6BDENN domain containing 6B. (590 aa)    
Predicted Functional Partners:
SUOX
Sulfite oxidase.
     
  0.748
RUSC2
RUN and SH3 domain containing 2.
      
 0.614
ACAP2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2.
      
 0.613
ENSNVIP00000002960
annotation not available
      
 0.563
ATP6V1F
ATPase H+ transporting V1 subunit F.
      
 0.532
OCRL
OCRL inositol polyphosphate-5-phosphatase.
      
 0.498
ENSNVIP00000006216
Microtubule associated monooxygenase, calponin and LIM domain containing 1.
      
 0.498
UACA
Uveal autoantigen with coiled-coil domains and ankyrin repeats.
      
 0.488
SDK1
Sidekick cell adhesion molecule 1.
      
 0.488
SDK2
Sidekick cell adhesion molecule 2.
      
 0.488
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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