Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AURKBAurora kinase B. (344 aa)    
Predicted Functional Partners:
CDCA8
Cell division cycle associated 8.
   
 0.996
BIRC5
Baculoviral IAP repeat containing 5.
   
 0.993
INCENP
Inner centromere protein.
   
 0.991
CCNA2
Cyclin A2.
   
 
 0.986
ENSNVIP00000014666
Cyclin dependent kinase 1.
  
0.978
CENPA
Centromere protein A.
   
 
 0.977
KIF11
Kinesin family member 11.
   
 
 0.961
NDC80
NDC80 kinetochore complex component.
   
 
 0.957
KIF20A
Kinesin family member 20A.
   
 
 0.953
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.950
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
Server load: low (16%) [HD]