Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DENND10DENN domain containing 10. (246 aa)    
Predicted Functional Partners:
ENSNVIP00000016155
COMM domain containing 8.
    
 
 0.973
COMMD4
COMM domain containing 4.
    
 
 0.973
ENSNVIP00000031449
COMM domain containing 5.
    
 
 0.973
ENSNVIP00000017424
COMM domain containing 2.
    
 
 0.972
ENSNVIP00000003147
Coiled-coil domain containing 93.
    
 
 0.969
VPS26C
VPS26 endosomal protein sorting factor C.
    
 
 0.969
CCDC22
Coiled-coil domain containing 22.
    
 
 0.968
COMMD1
Copper metabolism domain containing 1.
   
 
 0.967
COMMD6
COMM domain containing 6.
   
 
 0.961
COMMD10
COMM domain containing 10.
   
 
 0.960
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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