Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IRF2Interferon regulatory factor 2. (434 aa)    
Predicted Functional Partners:
IRF2BP2
Interferon regulatory factor 2 binding protein 2.
    
 
 0.930
IRF2BP1
Interferon regulatory factor 2 binding protein 1.
    
 
 0.908
IRF2BPL
Interferon regulatory factor 2 binding protein like.
    
 
 0.908
ENSNVIP00000023016
Interferon regulatory factor 1.
   
 0.901
ENSNVIP00000013359
TNF receptor associated factor 6.
    
 0.657
STAT1
Signal transducer and activator of transcription 1.
    
 0.640
ENSNVIP00000024373
Proliferating cell nuclear antigen.
   
 
 0.636
PRDM1
PR/SET domain 1.
    
 
 0.624
ENSNVIP00000028008
Replication factor C subunit 3.
   
 
 0.601
KAT2A
Lysine acetyltransferase 2A.
   
  0.542
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
Server load: low (6%) [HD]