Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IGFBP5Insulin like growth factor binding protein 5. (271 aa)    
Predicted Functional Partners:
ENSNVIP00000013151
Insulin like growth factor 1.
   
 0.966
PAPPA
Pappalysin 1.
    
 0.905
IGFALS
Insulin like growth factor binding protein acid labile subunit.
    
 0.886
PAPPA2
Pappalysin 2.
    
 0.801
IGF2
Insulin like growth factor 2.
   
 0.750
FAM20C
FAM20C golgi associated secretory pathway kinase.
    
 0.599
IGF1R
Insulin like growth factor 1 receptor.
   
 
 0.567
MRC1
Mannose receptor C-type 1.
    
   0.550
ENSNVIP00000026403
Mannan binding lectin serine peptidase 1.
   
 0.533
IGFBP3
Insulin like growth factor binding protein 3.
   
 
0.531
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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