Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NLRP6NLR family pyrin domain containing 6. (892 aa)    
Predicted Functional Partners:
ENSNVIP00000032327
PYD and CARD domain containing.
   
 0.954
ENSNVIP00000029154
annotation not available
   
 0.758
ENSNVIP00000029162
annotation not available
   
 0.758
ENSNVIP00000030314
MEFV innate immuity regulator, pyrin.
   
 0.749
PKP3
Plakophilin 3.
      
 0.742
CASP12
Caspase 12 (gene/pseudogene).
   
 0.727
DHX33
DEAH-box helicase 33.
     
 0.680
ENSNVIP00000014767
annotation not available
   
 0.651
ENSNVIP00000014842
annotation not available
   
 0.651
ENSNVIP00000014991
annotation not available
   
 0.651
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
Server load: low (12%) [HD]