Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IL12BInterleukin 12B. (329 aa)    
Predicted Functional Partners:
IL23A
Interleukin 23 subunit alpha.
  
 
 0.998
IL12A
Interleukin 12A.
    
 0.997
IL12RB1
Interleukin 12 receptor subunit beta 1.
    
 0.990
IL23R
Interleukin 23 receptor.
   
 0.987
JAK2
Janus kinase 2.
    
 0.982
IL12RB2
Interleukin 12 receptor subunit beta 2.
   
 0.973
IFNG
Interferon gamma.
  
 
 0.949
STAT3
Signal transducer and activator of transcription 3.
   
 0.946
TYK2
Tyrosine kinase 2.
    
 0.944
IL6
Interleukin 6.
     
 0.918
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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