Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADAM23ADAM metallopeptidase domain 23. (833 aa)    
Predicted Functional Partners:
LGI2
Leucine rich repeat LGI family member 2.
     
 0.968
ENSNVIP00000003284
Leucine rich glioma inactivated 1.
   
 0.879
ADAM22
ADAM metallopeptidase domain 22.
   
 0.851
NHLRC1
NHL repeat containing E3 ubiquitin protein ligase 1.
      
 0.753
ADAM11
ADAM metallopeptidase domain 11.
   
 0.741
LGI3
Leucine rich repeat LGI family member 3.
   
 
 0.729
LGI4
Leucine rich repeat LGI family member 4.
     
 0.698
ENSNVIP00000024972
Myeloid leukemia factor 1.
      
 0.588
SENP6
SUMO specific peptidase 6.
    
   0.586
RAPGEF5
Rap guanine nucleotide exchange factor 5.
      
 0.556
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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