Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSNVIP00000006795X-ray repair cross complementing 5. (733 aa)    
Predicted Functional Partners:
XRCC6
X-ray repair cross complementing 6.
  
 0.999
PRKDC
Protein kinase, DNA-activated, catalytic subunit.
   
 0.997
LIG4
DNA ligase 4.
   
 0.991
DCLRE1C
DNA cross-link repair 1C.
    
 0.989
ATM
ATM serine/threonine kinase.
    
 0.984
PARP1
poly(ADP-ribose) polymerase 1.
   
 
 0.966
MRE11
MRE11 homolog, double strand break repair nuclease.
   
 0.963
POLL
DNA polymerase lambda.
    
 0.952
ENSNVIP00000022866
annotation not available
    
 0.947
WRN
WRN RecQ like helicase.
   
 
 0.944
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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