Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SIGIRRSingle Ig and TIR domain containing. (358 aa)    
Predicted Functional Partners:
UNC79
Unc-79 homolog, NALCN channel complex subunit.
    
 0.628
TOLLIP
Toll interacting protein.
     
 0.626
MYD88
MYD88 innate immune signal transduction adaptor.
    
 0.548
IRAK1
Interleukin 1 receptor associated kinase 1.
    
 0.535
RUVBL1
RuvB like AAA ATPase 1.
    
 0.524
IRAK3
Interleukin 1 receptor associated kinase 3.
    
 0.520
RAG1
Recombination activating 1.
    
 0.515
LRRC25
Leucine rich repeat containing 25.
    
 0.507
ENSNVIP00000018597
Toll like receptor 2.
    
 
 0.502
TADA3
Transcriptional adaptor 3.
    
 0.498
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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