STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIRAS1DIRAS family GTPase 1. (198 aa)    
Predicted Functional Partners:
RAPGEF4
Rap guanine nucleotide exchange factor 4.
   
 0.752
PIK3CB
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta.
    
 0.741
ITSN2
Intersectin 2.
   
 0.613
RAPGEF2
Rap guanine nucleotide exchange factor 2.
    
 0.601
ENSNVIP00000024539
annotation not available
    
 0.601
AFDN
Afadin, adherens junction formation factor.
    
 0.598
ENSNVIP00000031513
annotation not available
    
 0.585
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
    
 0.584
ARAF
A-Raf proto-oncogene, serine/threonine kinase.
    
 0.584
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
    
 0.584
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.