STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIRAS1DIRAS family GTPase 1. (198 aa)    
Predicted Functional Partners:
ITSN2
Intersectin 2.
    
 0.876
ITSN1
Intersectin 1.
    
 0.808
SCIMP
SLP adaptor and CSK interacting membrane protein.
   
    0.735
PIK3CB
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta.
    
 0.729
RAPGEF4
Rap guanine nucleotide exchange factor 4.
    
 0.691
SHANK1
SH3 and multiple ankyrin repeat domains 1.
   
 0.662
ENSNVIP00000007724
annotation not available
    
 0.656
LAMTOR2
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2.
    
 0.625
MST1R
Macrophage stimulating 1 receptor.
   
 0.595
ENSNVIP00000003169
annotation not available
   
 0.595
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
Server load: low (28%) [HD]