STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHG5Pleckstrin homology and RhoGEF domain containing G5. (981 aa)    
Predicted Functional Partners:
ENSNVIP00000007208
Rho family GTPase 3.
    
 0.947
TNFSF15
TNF superfamily member 15.
    
 0.876
ENSNVIP00000013503
TNFRSF1A associated via death domain.
    
 0.868
FADD
Fas associated via death domain.
   
 0.853
ENSNVIP00000021095
Tumor necrosis factor.
    
 0.851
ARHGEF12
Rho guanine nucleotide exchange factor 12.
    
 0.840
ARHGEF11
Rho guanine nucleotide exchange factor 11.
    
 0.840
RIPK1
Receptor interacting serine/threonine kinase 1.
   
 0.834
YWHAE
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon.
    
 
 0.833
RND1
Rho family GTPase 1.
    
 0.817
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.