Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LRP2LDL receptor related protein 2. (4700 aa)    
Predicted Functional Partners:
LDLRAP1
Low density lipoprotein receptor adaptor protein 1.
    
 0.992
LRPAP1
LDL receptor related protein associated protein 1.
    
 0.990
CUBN
Cubilin.
   
 0.982
DAB2
DAB adaptor protein 2.
    
 0.963
LRP1
LDL receptor related protein 1.
    
  0.954
APOE
Apolipoprotein E.
    
 0.936
ANKRA2
Ankyrin repeat family A member 2.
    
 0.920
PTCH1
Patched 1.
    
 0.908
CLU
Clusterin.
    
 
 0.907
LRP1B
LDL receptor related protein 1B.
    
  0.907
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
Server load: low (14%) [HD]