Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSNVIP00000006977SMC5-SMC6 complex localization factor 1. (1070 aa)    
Predicted Functional Partners:
WRN
WRN RecQ like helicase.
   
 0.957
RAD18
RAD18 E3 ubiquitin protein ligase.
   
 
 0.953
ATR
ATR serine/threonine kinase.
    
 0.952
BARD1
BRCA1 associated RING domain 1.
   
 0.920
PSMD12
Proteasome 26S subunit, non-ATPase 12.
    
 0.905
CDC45
Cell division cycle 45.
   
 
 0.905
TP53BP1
Tumor protein p53 binding protein 1.
    
 0.902
RAD17
RAD17 checkpoint clamp loader component.
   
 0.900
RAD1
RAD1 checkpoint DNA exonuclease.
    
 0.897
MCM5
Minichromosome maintenance complex component 5.
   
 
 0.892
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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