Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VAC14VAC14 component of PIKFYVE complex. (785 aa)    
Predicted Functional Partners:
ENSNVIP00000006460
FIG4 phosphoinositide 5-phosphatase.
   
 0.999
PIKFYVE
Phosphoinositide kinase, FYVE-type zinc finger containing.
    
 0.998
DIPK2A
Divergent protein kinase domain 2A.
   
 0.905
WIPI2
WD repeat domain, phosphoinositide interacting 2.
    
 
 0.792
WIPI1
WD repeat domain, phosphoinositide interacting 1.
    
 
 0.792
STK40
Serine/threonine kinase 40.
   
 
 0.756
SOAT1
Sterol O-acyltransferase 1.
      
 0.754
DNAJB4
DnaJ heat shock protein family (Hsp40) member B4.
      
 0.754
USP33
Ubiquitin specific peptidase 33.
      
 0.754
POLR3E
RNA polymerase III subunit E.
      
 0.724
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.