Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
MAPK8Mitogen-activated protein kinase 8. (427 aa)    
Predicted Functional Partners:
MAPK9
Mitogen-activated protein kinase 9.
   
 0.991
JUN
Jun proto-oncogene, AP-1 transcription factor subunit.
   
 0.983
FOSL1
FOS like 1, AP-1 transcription factor subunit.
   
 0.981
MAPK8IP1
Mitogen-activated protein kinase 8 interacting protein 1.
   
 0.976
MAP2K4
Mitogen-activated protein kinase kinase 4.
   
 0.974
TP53
Tumor protein p53.
    
 0.973
MAP2K7
Mitogen-activated protein kinase kinase 7.
   
 0.970
MAP3K1
Mitogen-activated protein kinase kinase kinase 1.
    
 0.965
BCL2L1
BCL2 like 1.
    
 0.965
MAPK8IP3
Mitogen-activated protein kinase 8 interacting protein 3.
   
 0.962
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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