STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BACE1Beta-secretase 1. (501 aa)    
Predicted Functional Partners:
RTN3
Reticulon 3.
   
 0.969
RTN4
Reticulon 4.
   
 0.967
APP
Amyloid beta precursor protein.
    
 0.952
BACE2
Beta-secretase 2.
  
  
 
0.924
IDE
Insulin degrading enzyme.
     
 0.863
APLP2
Amyloid beta precursor like protein 2.
    
 0.850
GGA1
Golgi associated, gamma adaptin ear containing, ARF binding protein 1.
    
 0.807
ENSNVIP00000003900
annotation not available
    
 0.807
PSEN1
Presenilin 1.
    
 
 0.807
MMEL1
Membrane metalloendopeptidase like 1.
      
 0.793
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.