Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BACE1Beta-secretase 1. (501 aa)    
Predicted Functional Partners:
APP
Amyloid beta precursor protein.
    
 0.991
RTN3
Reticulon 3.
    
 0.946
RTN4
Reticulon 4.
    
 0.939
GGA1
Golgi associated, gamma adaptin ear containing, ARF binding protein 1.
    
 0.893
ENSNVIP00000003900
annotation not available
    
 0.893
BACE2
Beta-secretase 2.
     
  0.882
APLP2
Amyloid beta precursor like protein 2.
    
 0.859
IDE
Insulin degrading enzyme.
     
 0.843
GGA3
Golgi associated, gamma adaptin ear containing, ARF binding protein 3.
    
 0.838
PSEN1
Presenilin 1.
    
 
 0.815
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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