Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TMIGD1Transmembrane and immunoglobulin domain containing 1. (261 aa)    
Predicted Functional Partners:
GUCA2A
Guanylate cyclase activator 2A.
   
  
 0.932
OTOP3
Otopetrin 3.
      
 0.573
GUCA2B
Guanylate cyclase activator 2B.
   
  
 0.565
ENSNVIP00000011295
Clarin 3.
   
  
 0.560
PKHD1
PKHD1 ciliary IPT domain containing fibrocystin/polyductin.
      
 0.554
MRM3
Mitochondrial rRNA methyltransferase 3.
      
 0.538
ENSNVIP00000024034
Solute carrier family 10 member 2.
   
  
 0.537
ENSNVIP00000032271
Solute carrier family 10 member 6.
   
  
 0.537
TMEM86B
Transmembrane protein 86B.
      
 0.451
NKX1-1
NK1 homeobox 1.
      
 0.443
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
Server load: low (12%) [HD]