Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RAPGEF3Rap guanine nucleotide exchange factor 3. (903 aa)    
Predicted Functional Partners:
ENSNVIP00000001371
RAP1A, member of RAS oncogene family.
    
 0.943
RAP1B
RAP1B, member of RAS oncogene family.
    
 0.943
RIMS2
Regulating synaptic membrane exocytosis 2.
   
 0.924
ADCY8
Adenylate cyclase 8.
   
 
 0.915
ADCY2
Adenylate cyclase 2.
   
 
 0.904
ADCY4
Adenylate cyclase 4.
   
 
 0.903
ADCY6
Adenylate cyclase 6.
   
 
 0.902
ADCY5
Adenylate cyclase 5.
   
 
 0.902
ABCC8
ATP binding cassette subfamily C member 8.
    
 0.902
ADCY9
Adenylate cyclase 9.
   
 
 0.895
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.