PALB2 protein (Neovison vison) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PALB2

Partner and localizer of BRCA2. (1157 aa)

Predicted Functional Partners:

BRCA2

0.999

BRCA1

0.998

NDUFB5

0.995

NDUFB9

0.994

NDUFA12

0.994

ENSNVIP00000021678

0.994

NDUFS6

0.994

NDUFS4

0.993

ENSNVIP00000024326

0.993

ENSNVIP00000001223

0.992

Your Current Organism:

Neovison vison

NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BRCA1	BRCA2	ENSNVIP00000018001	ENSNVIP00000027714	BRCA1 DNA repair associated.	BRCA2 DNA repair associated.	0.999
BRCA1	ENSNVIP00000021678	ENSNVIP00000018001	ENSNVIP00000021678	BRCA1 DNA repair associated.	annotation not available	0.997
BRCA1	PALB2	ENSNVIP00000018001	ENSNVIP00000007227	BRCA1 DNA repair associated.	Partner and localizer of BRCA2.	0.998
BRCA2	BRCA1	ENSNVIP00000027714	ENSNVIP00000018001	BRCA2 DNA repair associated.	BRCA1 DNA repair associated.	0.999
BRCA2	ENSNVIP00000021678	ENSNVIP00000027714	ENSNVIP00000021678	BRCA2 DNA repair associated.	annotation not available	0.998
BRCA2	PALB2	ENSNVIP00000027714	ENSNVIP00000007227	BRCA2 DNA repair associated.	Partner and localizer of BRCA2.	0.999
ENSNVIP00000001223	ENSNVIP00000024326	ENSNVIP00000001223	ENSNVIP00000024326	annotation not available	annotation not available	0.999
ENSNVIP00000001223	NDUFA12	ENSNVIP00000001223	ENSNVIP00000009190	annotation not available	NADH:ubiquinone oxidoreductase subunit A12.	0.999
ENSNVIP00000001223	NDUFB5	ENSNVIP00000001223	ENSNVIP00000022480	annotation not available	NADH:ubiquinone oxidoreductase subunit B5.	0.999
ENSNVIP00000001223	NDUFB9	ENSNVIP00000001223	ENSNVIP00000002104	annotation not available	NADH:ubiquinone oxidoreductase subunit B9.	0.999
ENSNVIP00000001223	NDUFS4	ENSNVIP00000001223	ENSNVIP00000003151	annotation not available	NADH:ubiquinone oxidoreductase subunit S4.	0.999
ENSNVIP00000001223	NDUFS6	ENSNVIP00000001223	ENSNVIP00000031692	annotation not available	NADH:ubiquinone oxidoreductase subunit S6.	0.999
ENSNVIP00000001223	PALB2	ENSNVIP00000001223	ENSNVIP00000007227	annotation not available	Partner and localizer of BRCA2.	0.992
ENSNVIP00000021678	BRCA1	ENSNVIP00000021678	ENSNVIP00000018001	annotation not available	BRCA1 DNA repair associated.	0.997
ENSNVIP00000021678	BRCA2	ENSNVIP00000021678	ENSNVIP00000027714	annotation not available	BRCA2 DNA repair associated.	0.998
ENSNVIP00000021678	PALB2	ENSNVIP00000021678	ENSNVIP00000007227	annotation not available	Partner and localizer of BRCA2.	0.994
ENSNVIP00000024326	ENSNVIP00000001223	ENSNVIP00000024326	ENSNVIP00000001223	annotation not available	annotation not available	0.999
ENSNVIP00000024326	NDUFA12	ENSNVIP00000024326	ENSNVIP00000009190	annotation not available	NADH:ubiquinone oxidoreductase subunit A12.	0.999
ENSNVIP00000024326	NDUFB5	ENSNVIP00000024326	ENSNVIP00000022480	annotation not available	NADH:ubiquinone oxidoreductase subunit B5.	0.999
ENSNVIP00000024326	NDUFB9	ENSNVIP00000024326	ENSNVIP00000002104	annotation not available	NADH:ubiquinone oxidoreductase subunit B9.	0.999